Margaretha Van der Mey

Novel Selective PDE4 Inhibitors. 1. Synthesis, Structure−Activity Relationships, and Molecular Modeling of 4-(3,4-Dimethoxyphenyl)-2<i>H</i>-phthalazin-1-ones and Analogues

Margaretha Van der Mey, Armin Hatzelmann, Ivonne J. Van der Laan et al. · Journal of Medicinal Chemistry · 2001 · 74 citations · Full text

Synthesis and Structure−Activity Relationships of<i>cis</i>-Tetrahydrophthalazinone/Pyridazinone Hybrids:  A Novel Series of Potent Dual PDE3/PDE4 Inhibitory Agents

Margaretha Van der Mey, Kirsten M. Bommelé, Hildegard Boss et al. · Journal of Medicinal Chemistry · 2003 · 65 citations · Full text

Organic Chemistry, Pharmacotherapy, New Series +16

Novel Selective PDE4 Inhibitors. 2. Synthesis and Structure−Activity Relationships of 4-Aryl-Substituted <i>cis</i>-Tetra- and <i>cis</i>-Hexahydrophthalazinones

Margaretha Van der Mey, Armin Hatzelmann, G.P.M. Van Klink et al. · Journal of Medicinal Chemistry · 2001 · 53 citations · Full text

Novel Selective Phosphodiesterase (PDE4) Inhibitors. 4. Resolution, Absolute Configuration, and PDE4 Inhibitory Activity of <i>cis</i>-Tetra- and <i>cis</i>-Hexahydrophthalazinones

Margaretha Van der Mey, Hildegard Boss, Dennis Couwenberg et al. · Journal of Medicinal Chemistry · 2002 · 41 citations · Full text

Combinatorial Chemistry, Organic Chemistry, Chemistry +19

Novel Selective PDE4 Inhibitors. 3. <i>In Vivo</i> Antiinflammatory Activity of a New Series of N-Substituted <i>cis</i>-Tetra- and <i>cis</i>-Hexahydrophthalazinones

Margaretha Van der Mey, Hildegard Boss, Armin Hatzelmann et al. · Journal of Medicinal Chemistry · 2002 · 17 citations · Full text

Oral Application, Molecular Pharmacology, Medicinal Chemistry +12