Matthew L. Pearn

Loss of Caveolin-1 Accelerates Neurodegeneration and Aging

Brian P. Head, Jason N. Peart, Mathivadhani Panneerselvam et al. · PLoS ONE · 2010 · 184 citations · Full text

Amyloid precursor protein–mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration

Wei Xu, April M. Weissmiller, Joseph White et al. · Journal of Clinical Investigation · 2016 · 179 citations · Full text

Endocytic Pathway Disruption, Neurochemical Biomarkers, Synaptic Signaling +25

Propofol Neurotoxicity Is Mediated by p75 Neurotrophin Receptor Activation

Matthew L. Pearn, Yue Hu, Ingrid R. Niesman et al. · Anesthesiology · 2011 · 141 citations · Full text

Isoflurane Neurotoxicity Is Mediated by p75NTR-RhoA Activation and Actin Depolymerization

Brian P. Lemkuil, Brian P. Head, Matthew L. Pearn et al. · Anesthesiology · 2010 · 118 citations · Full text

Targeting increased levels of APP in Down syndrome: Posiphen‐mediated reductions in APP and its products reverse endosomal phenotypes in the Ts65Dn mouse model

Xu‐Qiao Chen, Ahmad Salehi, Matthew L. Pearn et al. · Alzheimer s & Dementia · 2020 · 52 citations · Full text