A 3D human triculture system modeling neurodegeneration and neuroinflammation in Alzheimer’s disease

Joseph Park, Isaac Wetzel, Ian Marriott, +5

Nature Neuroscience

Neurodegenerative DiseasesAlzheimer's DiseaseComputational NeuroscienceMedicineHuman Triculture System +7

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain

Shuko Takeda, Susanne Wegmann, Hansang Cho, +12

Nature Communications

Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease

Amanda McQuade, You Jung Kang, Jonathan Hasselmann, +19

Nature Communications

How the capillary burst microvalve works

Hansang Cho, Ho‐Young Kim, Ji Yoon Kang, +1

Journal of Colloid and Interface Science

EngineeringMicrofabricationFluid MechanicsCapillarity PhenomenonMicroscale System +4

Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer’s disease via H2O2− production

Heejung Chun, Hyeonjoo Im, You Jung Kang, +24

Nature Neuroscience

Neurodegenerative DiseasesAlzheimer's DiseasePathological HallmarksDegenerative PathologyBrain-immune Interaction +10

Aptamer-Based SERRS Sensor for Thrombin Detection

Hansang Cho, Brian R. Baker, Sebastian Wachsmann‐Hogiu, +5

Nano Letters

EngineeringSurface-enhanced Raman ScatteringBiomedical EngineeringNucleic Acid BiomarkersThrombosis +21

Three-Dimensional Blood-Brain Barrier Model for in vitro Studies of Neurovascular Pathology

Hansang Cho, Ji Hae Seo, Keith H.K. Wong, +6

Scientific Reports

An Air Particulate Pollutant Induces Neuroinflammation and Neurodegeneration in Human Brain Models

You Jung Kang, Hsih Yin Tan, Charles Y. Lee, +1

Advanced Science

ImmunologyAir QualityHuman Brain ModelsInnate ImmunitySocial Sciences +16

Migration of neutrophils targeting amyloid plaques in Alzheimer's disease mouse model

Sung-Hoon Baik, Moon-Yong Cha, Young‐Min Hyun, +11

Neurobiology of Aging

InflammationAlzheimer's DiseaseAmyloid PlaquesDementiaImmunology +7

Single-Step Nanoplasmonic VEGF₁₆₅ Aptasensor for Early Cancer Diagnosis

Hansang Cho, Erh-Chia Yeh, Raghu Sinha, +3

ACS Nano

NanotherapeuticsEngineeringCancer AngiogenesisBiomedical EngineeringNanomedicine +20