Evolution of Lipopolysaccharide (LPS) Recognition and Signaling: Fish TLR4 Does Not Recognize LPS and Negatively Regulates NF-κB Activation

María P. Sepulcre, Francisca Alcaraz‐Pérez, Azucena López‐Muñoz, +4

The Journal of Immunology

Innate Immune SystemImmunologyInnate ImmunityInflammationToll-like Receptors +21

Evolution of the Inflammatory Response in Vertebrates: Fish TNF-α Is a Powerful Activator of Endothelial Cells but Hardly Activates Phagocytes

Francisco J. Roca, Iván Mulero, Azucena López‐Muñoz, +4

The Journal of Immunology

New Insights into the Evolution of IFNs: Zebrafish Group II IFNs Induce a Rapid and Transient Expression of IFN-Dependent Genes and Display Powerful Antiviral Activities

Azucena López‐Muñoz, Francisco J. Roca, José Meseguer, +1

The Journal of Immunology

Evolution of inflammasome functions in vertebrates: Inflammasome and caspase-1 trigger fish macrophage cell death but are dispensable for the processing of IL-1β

Diego Angosto-Bazarra, Gloria López‐Castejón, Azucena López‐Muñoz, +4

Innate Immunity

Innate Immune SystemImmunologyImmune RegulationCell DeathPathology +22

Inflammasome Regulates Hematopoiesis through Cleavage of the Master Erythroid Transcription Factor GATA1

Sylwia D. Tyrkalska, Ana B. Pérez‐Oliva, Lola Rodríguez‐Ruiz, +15

Immunity

InflammationDevelopmental BiologyCell RegulationInflammasome Regulates HematopoiesisImmunology +6

Zebrafish larvae are unable to mount a protective antiviral response against waterborne infection by spring viremia of carp virus

Azucena López‐Muñoz, Francisco J. Roca, María P. Sepulcre, +2

Developmental & Comparative Immunology

Zebrafish LarvaeCarp VirusPathogenesisImmunologyWaterborne Infection +6

ATP Modulates Acute Inflammation In Vivo through Dual Oxidase 1–Derived H2O2 Production and NF-κB Activation

Sofía de Oliveira, Azucena López‐Muñoz, Sergio Candel, +3

The Journal of Immunology

Tnfa Signaling Through Tnfr2 Protects Skin Against Oxidative Stress–Induced Inflammation

Sergio Candel, Sofía de Oliveira, Azucena López‐Muñoz, +11

PLoS Biology

Inflammatory Lung DiseaseTnfα/tnfr2 AxisImmunologyImmune RegulationTnfα Antagonist Therapy +20

NAMPT-derived NAD+ fuels PARP1 to promote skin inflammation through parthanatos cell death

Francisco J. Martínez-Morcillo, Joaquín Cantón-Sandoval, Francisco J. Martínez‐Navarro, +15

PLoS Biology

Evolutionary conserved pro-inflammatory and antigen presentation functions of zebrafish IFNγ revealed by transcriptomic and functional analysis

Azucena López‐Muñoz, María P. Sepulcre, Francisco J. Roca, +3

Molecular Immunology

InflammationImmunogeneticsInnate Immune SystemImmunologyImmune Regulation +9