Mohammed Khaled Bin Break

Synthesis, characterization and biological activity of two Schiff base ligands and their nickel(II), copper(II), zinc(II) and cadmium(II) complexes derived from S-4-picolyldithiocarbazate and X-ray crystal structure of cadmium(II) complex derived from pyridine-2-carboxaldehyde

Teng-Jin Khoo, Mohammed Khaled Bin Break, Karen A. Crouse et al. · Inorganica Chimica Acta · 2014 · 77 citations

Biological Activity, Inorganic Chemistry, Biochemistry +8

Discovery of a highly active anticancer analogue of cardamonin that acts as an inducer of caspase-dependent apoptosis and modulator of the mTOR pathway

Mohammed Khaled Bin Break, Md Shahadat Hossan, Yivonn Khoo et al. · Fitoterapia · 2018 · 33 citations · Full text

Medicinal Chemistry, Active Anticancer Analogue, Medicine +10

Cytotoxic Activity of <i>Boesenbergia rotunda</i> Extracts against Nasopharyngeal Carcinoma Cells (HK1). Cardamonin, a <i>Boesenbergia rotunda</i> Constituent, Inhibits Growth and Migration of HK1 Cells by Inducing Caspase-Dependent Apoptosis and G2/M–Phase Arrest

Mohammed Khaled Bin Break, Michelle Chiang, Christophe Wiart et al. · Nutrition and Cancer · 2020 · 24 citations

Novel Semi-Synthetic Cu (II)–Cardamonin Complex Exerts Potent Anticancer Activity against Triple-Negative Breast and Pancreatic Cancer Cells via Inhibition of the Akt Signaling Pathway

Md Shahadat Hossan, Mohammed Khaled Bin Break, Tracey D. Bradshaw et al. · Molecules · 2021 · 22 citations · Full text

Discovery of novel indene-based hybrids as breast cancer inhibitors targeting Hsp90: Synthesis, bio-evaluation and molecular docking study

Amal M. Alosaimy, Amr S. Abouzied, Amani M.R. Alsaedi et al. · Arabian Journal of Chemistry · 2023 · 21 citations · Full text

Chemoprevention Strategy, Molecular Biology, Heat-shock Protein 90 +24