John Freedman

Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-α production in vivo

Rukhsana Aslam, Edwin R. Speck, Michael D. Kim et al. · Blood · 2005 · 475 citations · Full text

Life Sciences, Hematology, Immunology +16

Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia

June Li, Dianne E. van der Wal, Guangheng Zhu et al. · Nature Communications · 2015 · 376 citations · Full text

Medicine, Hematology, Immunology +17

Differences in serum cytokine levels in acute and chronic autoimmune thrombocytopenic purpura: relationship to platelet phenotype and antiplatelet T-cell reactivity

JW Semple, YP Milev, Donna Cosgrave et al. · Blood · 1996 · 363 citations · Full text

Medicine, Hematology, Immunology +13

Intravenous immunoglobulin ameliorates ITP via activating Fcγ receptors on dendritic cells

Vinayakumar Siragam, Andrew R. Crow, Davor Brinc et al. · Nature Medicine · 2006 · 245 citations

Life Sciences, Cell Biology, Immunology +16

A murine model of severe immune thrombocytopenia is induced by antibody- and CD8+ T cell–mediated responses that are differentially sensitive to therapy

Leola Chow, Rukhsana Aslam, Edwin R. Speck et al. · Blood · 2009 · 211 citations · Full text

Life Sciences, Hematology, Immunology +15