Roman J. Dorfman

A knowledge-based approach to generating diverse but energetically representative ensembles of ligand conformers

Roman J. Dorfman, K. M. Smith, Brian B. Masek et al. · Journal of Computer-Aided Molecular Design · 2007 · 20 citations

Engineering, Medicine, Knowledge-based Approach +11

Structural Unit Analysis Identifies Lead Series and Facilitates Scaffold Hopping in Combinatorial Chemistry

Philippa R. N. Wolohan, Lakshmi B. Akella, Roman J. Dorfman et al. · Journal of Chemical Information and Modeling · 2006 · 17 citations

Combinatorial Chemistry, Engineering, Hit Identification +24

Multistep Reaction Based De Novo Drug Design: Generating Synthetically Feasible Design Ideas

Brian B. Masek, David S. Baker, Roman J. Dorfman et al. · Journal of Chemical Information and Modeling · 2016 · 16 citations

Drug Target, Engineering, Synthetic Circuit +22