Near-infrared photoimmunotherapy of cancer: a new approach that kills cancer cells and enhances anti-cancer host immunity

Hisataka Kobayashi, Aki Furusawa, Adrian Rosenberg, +1

International Immunology

Combined CD44- and CD25-Targeted Near-Infrared Photoimmunotherapy Selectively Kills Cancer and Regulatory T Cells in Syngeneic Mouse Cancer Models

Yasuhiro Maruoka, Aki Furusawa, Ryuhei Okada, +7

Cancer Immunology Research

The Effect of Antibody Fragments on CD25 Targeted Regulatory T Cell Near-Infrared Photoimmunotherapy

Ryuhei Okada, Yasuhiro Maruoka, Aki Furusawa, +5

Bioconjugate Chemistry

An interdigit signalling centre instructs coordinate phalanx-joint formation governed by 5′Hoxd–Gli3 antagonism

Bau‐Lin Huang, Anna Trofka, Aki Furusawa, +6

Nature Communications

Treg-Dominant Tumor Microenvironment Is Responsible for Hyperprogressive Disease after PD-1 Blockade Therapy

Hiroaki Wakiyama, Takuya Kato, Aki Furusawa, +7

Cancer Immunology Research

Pd-1 Blockade TherapyPd-1 BlockadeImmunologyImmune RegulationImmunotherapeutics +23

Near-Infrared Photoimmunotherapy Combined with CTLA4 Checkpoint Blockade in Syngeneic Mouse Cancer Models

Yasuhiro Maruoka, Aki Furusawa, Ryuhei Okada, +7

Vaccines

Tumor ImmunologyCancer ImmunosurveillanceNir LightPhotodynamic TherapyMedicine +13

Local Depletion of Immune Checkpoint Ligand CTLA4 Expressing Cells in Tumor Beds Enhances Antitumor Host Immunity

Ryuhei Okada, Takuya Kato, Aki Furusawa, +4

Advanced Therapeutics

Near-infrared photoimmunotherapy targeting human-EGFR in a mouse tumor model simulating current and future clinical trials

Ryuhei Okada, Aki Furusawa, Daniel W. Vermeer, +8

EBioMedicine

Increased Immunogenicity of a Minimally Immunogenic Tumor after Cancer-Targeting Near Infrared Photoimmunotherapy

Hiroaki Wakiyama, Aki Furusawa, Ryuhei Okada, +5

Cancers

ImmunologyImmunotherapyTumor BiologyTumor ImmunologyOncology +14

Cyanine Phototruncation Enables Spatiotemporal Cell Labeling

Hiroshi Fukushima, Siddharth S. Matikonda, Syed Muhammad Usama, +6

Journal of the American Chemical Society