Müge Didem Orhan

Near-physiological-temperature serial crystallography reveals conformations of SARS-CoV-2 main protease active site for improved drug repurposing

Serdar Durdağı, Çağdaş Dağ, Berna Doğan et al. · Structure · 2021 · 44 citations · Full text

Integrating Ligand and Target-Driven Based Virtual Screening Approaches With in vitro Human Cell Line Models and Time-Resolved Fluorescence Resonance Energy Transfer Assay to Identify Novel Hit Compounds Against BCL-2

Gurbet Tutumlu, Berna Doğan, Timuçin Avşar et al. · Frontiers in Chemistry · 2020 · 34 citations · Full text

The neutralization effect of montelukast on SARS-CoV-2 is shown by multiscale in silico simulations and combined in vitro studies

Serdar Durdağı, Timuçin Avşar, Müge Didem Orhan et al. · Molecular Therapy · 2021 · 34 citations · Full text

An Integrated in silico Approach and in vitro Study for the Discovery of Small‐Molecule USP7 Inhibitors as Potential Cancer Therapies

Duaa Kanan, Tarek Kanan, Berna Doğan et al. · ChemMedChem · 2020 · 20 citations

Instant determination of the artemisinin from various <i>Artemisia annua L</i>. extracts by LC‐ESI‐MS/MS and their <i>in‐silico</i> modelling and <i>in vitro</i> antiviral activity studies against SARS‐CoV‐2

Kübra Dogan, Ebru Erol, Müge Didem Orhan et al. · Phytochemical Analysis · 2021 · 16 citations · Full text