Alexander R. Melrose

Phosphoproteomic quantitation and causal analysis reveal pathways in GPVI/ITAM-mediated platelet activation programs

Özgün Babur, Alexander R. Melrose, Jennifer M. Cunliffe et al. · Blood · 2020 · 85 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Assessment of the effects of Syk and BTK inhibitors on GPVI-mediated platelet signaling and function

Tony J. Zheng, Elizabeth R. Lofurno, Alexander R. Melrose et al. · American Journal of Physiology-Cell Physiology · 2021 · 38 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Effects of ex vivo blood anticoagulation and preanalytical processing time on the proteome content of platelets

Samuel Tassi Yunga, Austin Gower, Alexander R. Melrose et al. · Journal of Thrombosis and Haemostasis · 2022 · 32 citations · Full text

Medicine, Biochemistry, Hematology +12

The Toll-Like Receptor 2 Ligand Pam2CSK4 Activates Platelet Nuclear Factor-κB and Bruton’s Tyrosine Kinase Signaling to Promote Platelet-Endothelial Cell Interactions

Iván Parra‐Izquierdo, Hari Hara Sudhan Lakshmanan, Alexander R. Melrose et al. · Frontiers in Immunology · 2021 · 31 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Revised model of the tissue factor pathway of thrombin generation: Role of the feedback activation of FXI

Hari Hara Sudhan Lakshmanan, Aldrich Estonilo, Stéphanie E. Reitsma et al. · Journal of Thrombosis and Haemostasis · 2022 · 30 citations · Full text

Medicine, Biochemistry, Molecular Biology +16