Carole Pissot‐Soldermann

Discovery of a Dihydroisoquinolinone Derivative (NVP-CGM097): A Highly Potent and Selective MDM2 Inhibitor Undergoing Phase 1 Clinical Trials in p53wt Tumors

Philipp Holzer, Keiichi Masuya, Pascal Furet et al. · Journal of Medicinal Chemistry · 2015 · 202 citations · Full text

Dihydroisoquinolinone Derivative, Drug Target, Molecular Biology +18

Modulation of Activation-Loop Phosphorylation by JAK Inhibitors Is Binding Mode Dependent

Rita Andraos, Zhiyan Qian, Débora Bonenfant et al. · Cancer Discovery · 2012 · 126 citations · Full text

Crystal Structure, Molecular Biology, Signaling Pathway +21

Potent and Selective Inhibition of Polycythemia by the Quinoxaline JAK2 Inhibitor NVP-BSK805

Fabienne Baffert, Catherine H. Régnier, Alain De Pover et al. · Molecular Cancer Therapeutics · 2010 · 119 citations

Pharmacotherapy, Excellent Selectivity, Pharmaceutical Chemistry +20

An Asymmetric Synthesis of Hamigeran B via a Pd Asymmetric Allylic Alkylation for Enantiodiscrimination

Barry M. Trost, Carole Pissot‐Soldermann, Irwin Chen et al. · Journal of the American Chemical Society · 2004 · 96 citations

A Short and Concise Asymmetric Synthesis of Hamigeran B

Barry M. Trost, Carole Pissot‐Soldermann, Irwin Chen · Chemistry - A European Journal · 2004 · 57 citations

Cross-coupling Reaction, Bioorganic Chemistry, Biochemistry +11