Jean‐Michel Linget

Conversion of 4-cyanomethyl-pyrazole-3-carboxamides into CB1 antagonists with lowered propensity to pass the blood–brain-barrier

Jean‐Marie Receveur, Anthony Murray, Jean‐Michel Linget et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 48 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Lowered Propensity +9

Automation of metabolic stability studies in microsomes, cytosol and plasma using a 215 Gilson liquid handler

Jean‐Michel Linget, Pierre du Vignaud · Journal of Pharmaceutical and Biomedical Analysis · 1999 · 29 citations

Metabolic Stability Studies, Engineering, Biochemistry +10

Pretreatment of skin using an abrasive skin preparation pad, a microneedling device or iontophoresis improves absorption of methyl aminolevulinate in ex vivo human skin

Hanan Osman‐Ponchet, Alexandre Gaborit, Karine Sevin et al. · Photodiagnosis and Photodynamic Therapy · 2017 · 12 citations · Full text

Application of the Tissue Composition–Based Model to Minipig for Predicting the Volume of Distribution at Steady State and Dermis-to-Plasma Partition Coefficients of Drugs Used in the Physiologically Based Pharmacokinetics Model in Dermatology

Patrick Poulin, Séverine H. Collet, Nicolas Atrux‐Tallau et al. · Journal of Pharmaceutical Sciences · 2018 · 11 citations

Steady State, Pharmacokinetic Modeling, Physiologically-based Pharmacokinetic Modeling +9