Shigemi Terakubo

Molecular‐Size Reduction of a Potent CXCR4‐Chemokine Antagonist Using Orthogonal Combination of Conformation‐ and Sequence‐Based Libraries

Nobutaka Fujii, Shinya Oishi, Kenichi Hiramatsu et al. · Angewandte Chemie International Edition · 2003 · 204 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Enhancement of the T140-based pharmacophores leads to the development of more potent and bio-stable CXCR4 antagonistsElectronic supplementary information (ESI) available: Fig. S1: behaviors of TF14013, TF14016 and TF14013-Me in mouse serum; Fig. S2: behaviors of TF14002 (a), TF14005 (b), TF14006 (c), TF14013 (d), TF14016 (e) and TF14013 analogs (f) in rat liver homogenate; Table S1: characterization data of novel synthetic peptides; and HPLC charts for synthetic compounds of 4F-benzoyl-TE14011 (TF14013), 4F-benzoyl-TN14003 (TF14016), nicotinoyl-TE14011 (TF14031) and 4F-benzoyl-TE14011-Me (TF14013-Me), and for a degraded sample of 4F-benzoyl-TE14011 (TF14013) in rat liver homogenate and its co-injection with an authentic compound des-[Arg14-NH2]-4F-benzoyl-TE14011. See http://www.rsc.org/suppdata/ob/b3/b306613b/

Hirokazu Tamamura, Kenichi Hiramatsu, Makiko Mizumoto et al. · Organic & Biomolecular Chemistry · 2003 · 95 citations

Medicine, Medicinal Chemistry, Pharmacology +12

Stereoselective Synthesis of [<scp>l</scp>-Arg-<scp>l</scp>/<scp>d</scp>-3-(2-naphthyl)alanine]-Type (<i>E</i>)-Alkene Dipeptide Isosteres and Its Application to the Synthesis and Biological Evaluation of Pseudopeptide Analogues of the CXCR4 Antagonist FC131

Hirokazu Tamamura, Kenichi Hiramatsu, Satoshi Ueda et al. · Journal of Medicinal Chemistry · 2004 · 92 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Antiviral and Antitumor Activity of Licorice Root Extracts

Kunihiko Fukuchi, Noriyuki Okudaira, Kazunori Adachi et al. · In Vivo · 2016 · 90 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Proposal of Sphingomonas wittichii sp. nov. for strain RW1T, known as a dibenzo-p-dioxin metabolizer.

Eiko Yabuuchi, Hiroyuki Yamamoto, Shigemi Terakubo et al. · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · 2001 · 85 citations

Life Sciences, Microbiology, Molecular Biology +12