HIF1α is required for osteoclast activation by estrogen deficiency in postmenopausal osteoporosis

Yoshiteru Miyauchi, Yuiko Sato, Tami Kobayashi, +15

Proceedings of the National Academy of Sciences

Osteoclast stimulatory transmembrane protein and dendritic cell–specific transmembrane protein cooperatively modulate cell–cell fusion to form osteoclasts and foreign body giant cells

Hiroya Miyamoto, Takayuki Suzuki, Yoshiteru Miyauchi, +18

Journal of Bone and Mineral Research

Aldehyde-stress resulting from Aldh2 mutation promotes osteoporosis due to impaired osteoblastogenesis

Hiroko Hoshi, Hao Wu, Yoshinari Fujita, +25

Journal of Bone and Mineral Research

TNFα promotes osteosarcoma progression by maintaining tumor cells in an undifferentiated state

Takahiro Mori, Yuzo Sato, Kana Miyamoto, +13

Oncogene

Tumor BiologyAx Osteosarcoma CellsBone Morphogenic ProteinMedicineTnfα Treatment +11

Methotrexate inhibits osteoclastogenesis by decreasing RANKL-induced calcium influx into osteoclast progenitors

Hiroya Kanagawa, Ritsuko Masuyama, Mayu Morita, +14

Journal of Bone and Mineral Metabolism

Orthopaedic SurgeryBone Morphogenic ProteinBone RepairOsteoarthritisRankl-induced Calcium Influx +10

A serum metabolomics-based profile in low bone mineral density postmenopausal women

Takeshi Miyamoto, Akiyoshi Hirayama, Yuiko Sato, +18

Bone

Bone DiseaseMetabolic SyndromeBody CompositionBone HealthSerum Metabolomics-based Profile +11

Metabolomics-based profiles predictive of low bone mass in menopausal women

Takeshi Miyamoto, Akiyoshi Hirayama, Yuiko Sato, +14

Bone Reports

Metabolomic ProfilingGynecologyCompromised Bone StrengthOsteoporosisBone Disease +16

Factors affecting anterior knee pain following anatomic double‐bundle anterior cruciate ligament reconstruction

Yasuo Niki, Akihiro Hakozaki, Wataru Iwamoto, +4

Knee Surgery Sports Traumatology Arthroscopy

An Essential Role for STAT6-STAT1 Protein Signaling in Promoting Macrophage Cell-Cell Fusion

Hiroya Miyamoto, Eri Katsuyama, Yoshiteru Miyauchi, +14

Journal of Biological Chemistry

InflammationCytokineSignal TransductionEssential RoleSignaling Pathway +9

Interleukin-1 Receptor-associated Kinase-4 (IRAK4) Promotes Inflammatory Osteolysis by Activating Osteoclasts and Inhibiting Formation of Foreign Body Giant Cells

Eri Katsuyama, Hiroya Miyamoto, Tami Kobayashi, +13

Journal of Biological Chemistry

InflammationSclerostinInterleukin-1 Receptor-associated Kinase-4Inhibiting FormationBone Morphogenic Protein +8