CRISPR/Cas9‐mediated genome engineering: An adeno‐associated viral (AAV) vector toolbox

Elena Senís, Chronis Fatouros, Stefanie Große, +5

Biotechnology Journal

Systems BiologyEngineeringGenome SurgeryAav/crispr VectorsGenetic Engineering +13

Optogenetic control of nuclear protein export

Dominik Niopek, Pierre Wehler, Julia Roensch, +2

Nature Communications

Engineering light-inducible nuclear localization signals for precise spatiotemporal control of protein dynamics in living cells

Dominik Niopek, Dirk Benzinger, Julia Roensch, +4

Nature Communications

Biophysical ModelingMolecular RegulationMolecular BiologyLinus-mediated Nuclear ImportOptogenetics +18

Engineered anti-CRISPR proteins for optogenetic control of CRISPR–Cas9

Felix Bubeck, Mareike D. Hoffmann, Zander Harteveld, +11

Nature Methods

EngineeringSynthetic BiologyMolecular BiologyGenetic EngineeringAnti-crispr Proteins +5

Cell-specific CRISPR–Cas9 activation by microRNA-dependent expression of anti-CRISPR proteins

Mareike D. Hoffmann, Sabine Aschenbrenner, Kleopatra Rapti, +7

Nucleic Acids Research

Coupling Cas9 to artificial inhibitory domains enhances CRISPR-Cas9 target specificity

Sabine Aschenbrenner, Stefan M. Kallenberger, Mareike D. Hoffmann, +3

Science Advances

Off-target EffectEngineeringSpecific Genome EditingComputational BiologyMolecular Biology +11

AAV vector-mediated in vivo reprogramming into pluripotency

Elena Senís, Lluc Mosteiro, Stefan Wilkening, +10

Nature Communications

Robust RNAi enhancement via human Argonaute-2 overexpression from plasmids, viral vectors and cell lines

Kathleen Börner, Dominik Niopek, Gabriella Cotugno, +19

Nucleic Acids Research

Rna ProcessingSystems BiologyRna InterferenceMedicineNatural Sciences +13

Creating functional engineered variants of the single-module non-ribosomal peptide synthetase IndC by T domain exchange

Ralf Beer, Konrad Herbst, Nikolaos Ignatiadis, +18

Molecular BioSystems

Optogenetic control of <i>Neisseria meningitidis</i> Cas9 genome editing using an engineered, light-switchable anti-CRISPR protein

Mareike D. Hoffmann, Jan Mathony, Julius Upmeier zu Belzen, +7

Nucleic Acids Research

Nmecas9 ActivityEngineeringMolecular BiologyMolecular GeneticsLight-switchable Anti-crispr Protein +16