Sabine Aschenbrenner

Engineered anti-CRISPR proteins for optogenetic control of CRISPR–Cas9

Felix Bubeck, Mareike D. Hoffmann, Zander Harteveld et al. · Nature Methods · 2018 · 213 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Cell-specific CRISPR–Cas9 activation by microRNA-dependent expression of anti-CRISPR proteins

Mareike D. Hoffmann, Sabine Aschenbrenner, Kleopatra Rapti et al. · Nucleic Acids Research · 2019 · 116 citations · Full text

Life Sciences, Biotechnology, Molecular Genetics +17

Caspase-8 cleaves its substrates from the plasma membrane upon CD95-induced apoptosis

J. Beaudouin, Clarissa Liesche, Sabine Aschenbrenner et al. · Cell Death and Differentiation · 2013 · 73 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Coupling Cas9 to artificial inhibitory domains enhances CRISPR-Cas9 target specificity

Sabine Aschenbrenner, Stefan M. Kallenberger, Mareike D. Hoffmann et al. · Science Advances · 2020 · 66 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Optogenetic control of <i>Neisseria meningitidis</i> Cas9 genome editing using an engineered, light-switchable anti-CRISPR protein

Mareike D. Hoffmann, Jan Mathony, Julius Upmeier zu Belzen et al. · Nucleic Acids Research · 2020 · 45 citations · Full text

Life Sciences, Biotechnology, Genetics +14