Renato J. Scialis

Quantitative Contribution of Six Major Transporters to the Hepatic Uptake of Drugs: “SLC-Phenotyping” Using Primary Human Hepatocytes

Yi‐An Bi, Chester Costales, Sumathy Mathialagan et al. · Journal of Pharmacology and Experimental Therapeutics · 2019 · 77 citations · Full text

Positive Allosteric Modulation of AMPA Receptors from Efficacy to Toxicity: The Interspecies Exposure-Response Continuum of the Novel Potentiator PF-4778574

Christopher L. Shaffer, Raymond S Hurst, Renato J. Scialis et al. · Journal of Pharmacology and Experimental Therapeutics · 2013 · 61 citations

Mechanism-Based Pharmacokinetic Modeling to Evaluate Transporter-Enzyme Interplay in Drug Interactions and Pharmacogenetics of Glyburide

Manthena V. S. Varma, Renato J. Scialis, Jian Lin et al. · The AAPS Journal · 2014 · 57 citations · Full text

Drug Interactions, Pharmacokinetic Modeling, Biochemistry +9

Transporter‐Mediated Hepatic Uptake Plays an Important Role in the Pharmacokinetics and Drug–Drug Interactions of Montelukast

MV Varma, Emi Kimoto, Renato J. Scialis et al. · Clinical Pharmacology & Therapeutics · 2016 · 49 citations

Reliable Rate Measurements for Active and Passive Hepatic Uptake Using Plated Human Hepatocytes

Yi‐An Bi, Renato J. Scialis, Sarah Lazzaro et al. · The AAPS Journal · 2017 · 43 citations

Reliable Rate Measurements, Hepatology, Medicine +10