Brian K. Flesner

Clinical validation of a next-generation sequencing-based multi-cancer early detection “liquid biopsy” blood test in over 1,000 dogs using an independent testing set: The CANcer Detection in Dogs (CANDiD) study

Andi Flory, Kristina M. Kruglyak, John A. Tynan et al. · PLoS ONE · 2022 · 56 citations · Full text

Medicine, Oncology, Veterinary Oncology +17

Adjuvant Sirolimus Does Not Improve Outcome in Pet Dogs Receiving Standard-of-Care Therapy for Appendicular Osteosarcoma: A Prospective, Randomized Trial of 324 Dogs

Amy K. LeBlanc, Christina Mazcko, Aswini Cherukuri et al. · Clinical Cancer Research · 2021 · 54 citations · Full text

Medicine, Oncology, Pharmacology +17

Autologous cancer cell vaccination, adoptive T-cell transfer, and interleukin-2 administration results in long-term survival for companion dogs with osteosarcoma

Brian K. Flesner, Gary W. Wood, Pamela Gayheart‐Walsten et al. · Journal of Veterinary Internal Medicine · 2020 · 43 citations · Full text

Medicine, Immunology, Oncology +17

Long-Term Survival and Glycemic Control with Toceranib Phosphate and Prednisone for a Metastatic Canine Insulinoma

Brian K. Flesner, Jon M. Fletcher, Taylor Smithee et al. · Journal of the American Animal Hospital Association · 2018 · 31 citations · Full text

Medicine, Oncology, Veterinary Oncology +16

6-Thioguanine and zebularine down-regulate DNMT1 and globally demethylate canine malignant lymphoid cells

Brian K. Flesner, Senthil R. Kumar, Jeffrey N. Bryan · BMC Veterinary Research · 2014 · 21 citations · Full text

Medicine, Oncology, Pharmacology +13