Andrés A. Arias

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Qian Zhang, Paul Bastard, Zhiyong Liu et al. · Science · 2020 · 2.4K citations · Full text

Human Loci, Disease Susceptibility, Inborn Errors +14

Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

Paul Bastard, Adrian Gervais, Tom Le Voyer et al. · Science Immunology · 2021 · 600 citations · Full text

A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40phox and selective defects in neutrophil NADPH oxidase activity

Juan D. Matute, Andrés A. Arias, Nicola Wright et al. · Blood · 2009 · 414 citations · Full text

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19

Takaki Asano, Bertrand Boisson, Fanny Onodi et al. · Science Immunology · 2021 · 410 citations · Full text

Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease

Jacinta Bustamante, Andrés A. Arias, Guillaume Vogt et al. · Nature Immunology · 2011 · 280 citations · Full text

Medical Microbiology, Pulmonary Tuberculosis, Tuberculosis Prevention +9