Kyle W. Becker

Endosomolytic polymersomes increase the activity of cyclic dinucleotide STING agonists to enhance cancer immunotherapy

Daniel Shae, Kyle W. Becker, Plamen P. Christov et al. · Nature Nanotechnology · 2019 · 633 citations

Polymer-drug Conjugate, Cyclic Dinucleotide Sting, Immunology +7

Co-delivery of Peptide Neoantigens and Stimulator of Interferon Genes Agonists Enhances Response to Cancer Vaccines

Daniel Shae, Jessalyn J. Baljon, Mohamed Wehbe et al. · ACS Nano · 2020 · 153 citations · Full text

Mucosal Immunization with a pH-Responsive Nanoparticle Vaccine Induces Protective CD8⁺ Lung-Resident Memory T Cells

Frances C. Knight, Pavlo Gilchuk, Amrendra Kumar et al. · ACS Nano · 2019 · 127 citations · Full text

Nanoparticles, Engineering, Adaptive Immune System +19

Nanoparticle delivery improves the pharmacokinetic properties of cyclic dinucleotide STING agonists to open a therapeutic window for intravenous administration

Mohamed Wehbe, Lihong Wang-Bishop, Kyle W. Becker et al. · Journal of Controlled Release · 2020 · 112 citations · Full text

Nanomedicine, Engineering, Therapeutic Nanomaterials +9

STING-activating nanoparticles normalize the vascular-immune interface to potentiate cancer immunotherapy

Lihong Wang-Bishop, Blaise R. Kimmel, Verra M. Ngwa et al. · Science Immunology · 2023 · 106 citations · Full text

Nanoparticles, Engineering, Immunology +17