Insights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 protein

Dahai Luo, Ting Xu, R.P. Watson, +9

The EMBO Journal

Viral ReplicationNatural SciencesDna ReplicationMolecular BiologyVirology +8

Structure of the Dengue Virus Helicase/Nucleoside Triphosphatase Catalytic Domain at a Resolution of 2.4 A

Ting Xu, Aruna Sampath, Alex Chao, +5

Journal of Virology

Dengue virus NS4B interacts with NS3 and dissociates it from single-stranded RNA

Indira Umareddy, Alex Chao, Aruna Sampath, +2

Journal of General Virology

Dengue Virus ReplicationViral ReplicationDengue VirusMolecular BiologyViral Structural Protein +14

Both Rb and E7 are regulated by the ubiquitin proteasome pathway in HPV-containing cervical tumor cells

Jing Wang, Aruna Sampath, Pradip Raychaudhuri, +1

Oncogene

Cervical CancerCell RegulationUbiquitin Proteasome PathwayMedicinePathology +6

Structure-Based Mutational Analysis of the NS3 Helicase from Dengue Virus

Aruna Sampath, Ting Xu, Alex Chao, +3

Journal of Virology

Virus StructureCrystal StructureDengue VirusMolecular VirologyBiochemistry +11

Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4

Kelly L. Warfield, Emily M. Plummer, Andrew C. Sayce, +25

Antiviral Research

Dengue Virus Evolution under a Host-Targeted Antiviral

Emily M. Plummer, Michael D. Buck, Marisa Sanchez, +9

Journal of Virology

Finding New Medicines for Flaviviral Targets

Thomas H. Keller, Yen‐Liang Chen, John E. Knox, +7

Novartis Foundation symposium

Medicinal ChemistryNs3 ProteasesMedicineAntiviral Drug DevelopmentAntiviral Therapy +12

Humanized mouse model of glucose 6-phosphate dehydrogenase deficiency for in vivo assessment of hemolytic toxicity

Rosemary Rochford, Colin Ohrt, Paul Baresel, +5

Proceedings of the National Academy of Sciences

The Iminosugar UV-4 is a Broad Inhibitor of Influenza A and B Viruses ex Vivo and in Mice

Kelly L. Warfield, Dale L. Barnard, Sven Enterlein, +6

Viruses

Influenza BViral PathogenesisImmunologyImmunotherapeuticsFlu Vaccination +15