Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions

Ingo Bartholomäus, Naoto Kawakami, Francesca Odoardi, +8

Nature

Autoimmune DiseaseMedicineT-regulatory CellImmunologyPathology +8

T cells become licensed in the lung to enter the central nervous system

Francesca Odoardi, Christopher Sie, Kristina Streyl, +16

Nature

TracheobronchitisMedicineT-regulatory CellImmunologyAutoimmunity +6

Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid

Christian Schläger, Henrike Körner, Martin Krueger, +13

Nature

NeuroanatomyMedicineCerebrospinal FluidImmunologyCell Trafficking +10

Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis

Stefan A. Berghoff, Lena Spieth, Ting Sun, +25

Nature Neuroscience

InflammationNeuroregenerationMedicineBrain-immune InteractionNeuroprotection +8

Live imaging of effector cell trafficking and autoantigen recognition within the unfolding autoimmune encephalomyelitis lesion

Naoto Kawakami, U. Valentin Nägerl, Francesca Odoardi, +3

The Journal of Experimental Medicine

The lung microbiome regulates brain autoimmunity

Leon Hosang, Roger Cugota Canals, Felicia Joy van der Flier, +4

Nature

PsychoneuroimmunologyAutoimmune DiseaseInflammatory Lung DiseaseLung InflammationMedicine +6

The Activation Status of Neuroantigen-specific T Cells in the Target Organ Determines the Clinical Outcome of Autoimmune Encephalomyelitis

Naoto Kawakami, Zhaoxia Li, Francesca Odoardi, +12

The Journal of Experimental Medicine

Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein

Raquel Pinho, Isabel Paiva, Kristina Gotovac, +23

Human Molecular Genetics

GeneticsCell CycleTranscriptional RegulationAutophagyCellular Regulatory Mechanism +14

Dietary cholesterol promotes repair of demyelinated lesions in the adult brain

Stefan A. Berghoff, Nina Gerndt, Jan Winchenbach, +12

Nature Communications

A combination of fluorescent NFAT and H2B sensors uncovers dynamics of T cell activation in real time during CNS autoimmunity

Dmitri Lodygin, Francesca Odoardi, Christian Schläger, +7

Nature Medicine

Immunological MemorySignal TransductionAutoimmune DiseaseFluorescent NfatMedicine +12