Astrocytes initiate inflammation in the injured mouse spinal cord by promoting the entry of neutrophils and inflammatory monocytes in an IL-1 receptor/MyD88-dependent fashion

Isabelle Pineau, Libo Sun, Dominic Bastien, +1

Brain Behavior and Immunity

InflammationSpinal Cord InjuryAutoimmune DiseaseIl-1 Receptor/myd88-dependent FashionImmunology +5

P2X₄Receptors Influence Inflammasome Activation after Spinal Cord Injury

Juan Pablo de Rivero Vaccari, Dominic Bastien, Geoffrey Yurcisin, +5

Journal of Neuroscience

IL-1  Gene Deletion Protects Oligodendrocytes after Spinal Cord Injury through Upregulation of the Survival Factor Tox3

Dominic Bastien, Victor Bellver Landete, Martine Lessard, +6

Journal of Neuroscience

Multiple metabolic pathways fuel the truncated tricarboxylic acid cycle of the prostate to sustain constant citrate production and secretion

Lilianne Frégeau-Proulx, Aurélie Lacouture, Line Berthiaume, +14

Molecular Metabolism

The use of isomeric testosterone dimers to explore allosteric effects in substrate binding to cytochrome P450 CYP3A4

Ilia G. Denisov, Piotr J. Mak, Yelena V. Grinkova, +4

Journal of Inorganic Biochemistry

Molecular PharmacologySubstrate BindingBiochemistryMedicineNatural Sciences +7

Fragment-Based Design of Symmetrical Bis-benzimidazoles as Selective Inhibitors of the Trimethoprim-Resistant, Type II R67 Dihydrofolate Reductase

Dominic Bastien, Maximilian C. C. J. C. Ebert, Delphine Forge, +7

Journal of Medicinal Chemistry

Symmetrical Bis-benzimidazolesFragment-based DesignCombinatorial ChemistryDrug TargetSelective Inhibitors +20

Synthesis and preliminary in vitro biological evaluation of 7α-testosterone–chlorambucil hybrid designed for the treatment of prostate cancer

Dominic Bastien, Rana Hanna, Valérie Leblanc, +2

European Journal of Medicinal Chemistry

Anti-cancer AgentProstatic DiseaseVitro Biological EvaluationPharmacologyRadiation Oncology

A FACS-Free Purification Method to Study Estrogen Signaling, Organoid Formation, and Metabolic Reprogramming in Mammary Epithelial Cells

Aurélie Lacouture, Cynthia Jobin, Cindy Weidmann, +5

Frontiers in Endocrinology

A set of primers for amplification of mitochondrial DNA in <i>Picea abies</i> and other conifer species

Sylvain Jeandroz, Dominic Bastien, Anne Chandelier, +2

Molecular Ecology Notes

BotanyGeneticsOther Conifer SpeciesMolecular GeneticsGenomics +20

Characterization of a mosaic minisatellite locus in the mitochondrial DNA of Norway spruce [Picea abies (L.) Karst.]

Dominic Bastien, Julien Favre, A.M. Collignon, +2

Theoretical and Applied Genetics

BiologyGenetic DiversityPlant GeneticsMolecular EcologyMedicine +8