Concepedia

Author

Shengdong Ke

Columbia UniversityORCID

Also Known As

Ke, Shengdong, Sheng-Dong Ke, Shengdong Ke

17

Publications

2.4K

Citations

12

H-Index

14

Concepts

All Affiliations

Columbia UniversityRockefeller UniversityHoward Hughes Medical InstituteNew York Genome CenterJackson Laboratory
SK

About

Shengdong Ke is an author at Columbia University specializing in functional genomics, genetics, and medicine.

Top Concepts

#ConceptH-IndexPublicationsCitations

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Medicine

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77

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Functional Genomics

2

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77

3

Genetics

2

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77

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Developmental Biology

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Gene Expression

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Shengdong Ke

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12

Publications

2.4K

Citations

12

H-Index

YearCitations

A majority of m<sup>6</sup>A residues are in the last exons, allowing the potential for 3′ UTR regulation

Shengdong Ke, Endalkachew A. Alemu, Claudia Mertens,

Genes & Development

2015

814

m<sup>6</sup>A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover

Shengdong Ke, Amy Pandya‐Jones, Yuhki Saito,

Genes & Development

2017

565

Activated Expression of an<i>Arabidopsis</i>HD-START Protein Confers Drought Tolerance with Improved Root System and Reduced Stomatal Density  

Hong Yu, Xi Chen, Yuanyuan Hong,

The Plant Cell

2008

371

Quantitative evaluation of all hexamers as exonic splicing elements

Shengdong Ke, Shulian Shang, Sergey Kalachikov,

Genome Research

2011

231

Pre-mRNA processing includes <i>N</i><sup>6</sup> methylation of adenosine residues that are retained in mRNA exons and the fallacy of “RNA epigenetics”

Robert B. Darnell, Shengdong Ke, James Darnell

RNA

2017

78

Saturation mutagenesis reveals manifold determinants of exon definition

Shengdong Ke, Vincent Anquetil, Jorge Rojas Zamalloa,

Genome Research

2017

75

Exon-intron boundary inhibits m6A deposition, enabling m6A distribution hallmark, longer mRNA half-life and flexible protein coding

Zhiyuan Luo, Qilian Ma, Shan Sun,

Nature Communications

2023

56

Positive selection acting on splicing motifs reflects compensatory evolution

Shengdong Ke, Xiang H.-F. Zhang, Lawrence A. Chasin

Genome Research

2008

53

Splicing of designer exons reveals unexpected complexity in pre-mRNA splicing

Xiang H.-F. Zhang, Mauricio A. Arias, Shengdong Ke,

RNA

2009

49

Deep learning modeling m6A deposition reveals the importance of downstream cis-element sequences

Zhiyuan Luo, Jiacheng Zhang, Jingyi Fei,

Nature Communications

2022

33

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