Dong‐Ming Shen

Rapid Identification of Subtype-Selective Agonists of the Somatostatin Receptor Through Combinatorial Chemistry

Susan P. Rohrer, Elizabeth T. Birzin, Ralph T. Mosley et al. · Science · 1998 · 459 citations

Combinatorial Chemistry, Immunology, Pharmacotherapy +26

Discovery of Vibegron: A Potent and Selective β₃Adrenergic Receptor Agonist for the Treatment of Overactive Bladder

Scott D. Edmondson, Cheng Zhu, Nam Fung Kar et al. · Journal of Medicinal Chemistry · 2015 · 101 citations · Full text

DGAT2 Inhibition Alters Aspects of Triglyceride Metabolism in Rodents but Not in Non-human Primates

David G. McLaren, Seongah Han, Beth Murphy et al. · Cell Metabolism · 2018 · 82 citations

Metabolic Syndrome, Health Sciences, Biochemistry +12

Microscale High-Throughput Experimentation as an Enabling Technology in Drug Discovery: Application in the Discovery of (Piperidinyl)pyridinyl-1 <i>H</i> -benzimidazole Diacylglycerol Acyltransferase 1 Inhibitors

Tim Cernak, Nathan J. Gesmundo, Kevin D. Dykstra et al. · Journal of Medicinal Chemistry · 2017 · 81 citations · Full text

Versatile and Efficient Solid-Phase Syntheses of Pyrazoles and Isoxazoles

Dong‐Ming Shen, Min Shu, Kevin T. Chapman · Organic Letters · 2000 · 55 citations

Isomeric Pyrazoles, Isoxazoles 5, Derivatives +14