Microenvironments in Tuberculous Granulomas Are Delineated by Distinct Populations of Macrophage Subsets and Expression of Nitric Oxide Synthase and Arginase Isoforms

Joshua T. Mattila, Olabisi Ojo, Diane Kepka‐Lenhart, +10

The Journal of Immunology

Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control

Hannah P. Gideon, Travis K. Hughes, Constantine N. Tzouanas, +40

Immunity

Restrictive GranulomasMicrobial PathogensAdaptive Immune SystemImmunologyImmune Regulation +19

Macrophage Polarization Drives Granuloma Outcome during Mycobacterium tuberculosis Infection

Simeone Marino, Nicholas A. Cilfone, Joshua T. Mattila, +3

Infection and Immunity

Reactivation of Latent Tuberculosis in Cynomolgus Macaques Infected with SIV Is Associated with Early Peripheral T Cell Depletion and Not Virus Load

Collin R. Diedrich, Joshua T. Mattila, Edwin Klein, +6

PLoS ONE

Latent Mycobacterium TuberculosisPulmonary TuberculosisViral PersistenceCynomolgus Macaques InfectedLatent Tuberculosis +13

Activated B Cells in the Granulomas of Nonhuman Primates Infected with Mycobacterium tuberculosis

Jia Yao Phuah, Joshua T. Mattila, Philana Ling Lin, +1

American Journal Of Pathology

Neutrophils express pro- and anti-inflammatory cytokines in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques

Hannah P. Gideon, Jia Yao Phuah, Beth A. Fallert Junecko, +1

Mucosal Immunology

Mycobacterium Tuberculosis InfectionAdaptive Immune SystemCellular ImmunologyImmunologyImmune Regulation +24

CD4⁺Regulatory T Cells in a Cynomolgus Macaque Model of<i>Mycobacterium tuberculosis</i>Infection

Angela M. Green, Joshua T. Mattila, Carolyn Bigbee, +3

The Journal of Infectious Diseases

Lymph nodes are sites of prolonged bacterial persistence during Mycobacterium tuberculosis infection in macaques

Sharie Keanne C. Ganchua, Anthony M. Cadena, Pauline Maiello, +7

PLoS Pathogens

Mycobacterium Tuberculosis InfectionHumoral ResponseImmunologyPathologyFdg Avidity +15

CD8+ lymphocytes are critical for early control of tuberculosis in macaques

Caylin G. Winchell, Sarah K. Nyquist, Michael C. Chao, +24

The Journal of Experimental Medicine

Adaptive Immune SystemImmune RegulationImmunologyImmunodominanceFunctional Role +15

Simian Immunodeficiency Virus-Induced Changes in T Cell Cytokine Responses in Cynomolgus Macaques with Latent <i>Mycobacterium tuberculosis</i> Infection Are Associated with Timing of Reactivation

Joshua T. Mattila, Collin R. Diedrich, Philana Ling Lin, +2

The Journal of Immunology