Concepedia

R C Moschel

RC

Statistics

Publications

7

Citations

795

H-Index

7

Active since

1991

Affiliations

University of Chicago(Current)

The University of Texas Southwestern Medical Center

Pennsylvania State University

National Institutes of Health

R C Moschel is an author at University of Chicago specializing in medicine, pharmacology, and tumor biology.

Top concepts

Publications per year

1991–2001

7

Publications

7

Effect of O6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents.

M. Eileen Dolan, R. Brian Mitchell, Christine Mummert et al. · PubMed · 1991 · 228 citations

, , +16

Phase I trial of O6-benzylguanine for patients undergoing surgery for malignant glioma.

H. S. Friedman, Demetrius M. Kokkinakis, James M. Pluda et al. · Journal of Clinical Oncology · 1998 · 216 citations

Effect of O6-benzylguanine on the sensitivity of human tumor xenografts to 1,3-bis(2-chloroethyl)-1-nitrosourea and on DNA interstrand cross-link formation.

R. Brian Mitchell, R C Moschel, M E Dolan · PubMed · 1992 · 104 citations

, , +14

8-Substituted O6-Benzylguanine, Substituted 6(4)-(Benzyloxy)pyrimidine, and Related Derivatives as Inactivators of Human O6-Alkylguanine-DNA Alkyltransferase

Mi-Young Chae, Kristin Swenn, Sreenivas Kanugula et al. · Journal of Medicinal Chemistry · 1995 · 76 citations

Thresholds of O6-alkylguanine-DNA alkyltransferase which confer significant resistance of human glial tumor xenografts to treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea or temozolomide.

Demetrius M. Kokkinakis, Dora Bocangel, S. Clifford Schold et al. · PubMed · 2001 · 75 citations

, , +18

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