Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system

Antonis Koussounadis, Simon P. Langdon, In Hwa Um, +2

Scientific Reports

Systems Biology Reveals New Strategies for Personalizing Cancer Medicine and Confirms the Role of PTEN in Resistance to Trastuzumab

Dana Faratian, Alexey Goltsov, Galina Lebedeva, +8

Cancer Research

Pten Inhibitor BpCancer BiologyTumor BiologyOncologyReceptor Tyrosine Kinase +15

Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of<i>in vitro</i>breast cancer models

Carol Ward, James Meehan, Peter Mullen, +14

Oncotarget

Multi-Scale Genomic, Transcriptomic and Proteomic Analysis of Colorectal Cancer Cell Lines to Identify Novel Biomarkers

Romina Briffa, In Hwa Um, Dana Faratian, +4

PLoS ONE

EngineeringMulti-scale GenomicPathologyMultiomicsMyc Amplifications +21

Defining the molecular response to trastuzumab, pertuzumab and combination therapy in ovarian cancer

Andrew H. Sims, Annelien J.M. Zweemer, Yoko Nagumo, +8

British Journal of Cancer

Tissue-specific tolerance in fatal Covid-19

David A. Dorward, Clark D Russell, In Hwa Um, +24

Viral DiagnosticsLung InflammationImmunologyViral PathogenesisTissue-specific Tolerance +14

The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer

Rui Huang, Simon P. Langdon, Matthew Tse, +4

Oncotarget

Evaluation of the dual mTOR/PI3K inhibitors Gedatolisib (PF-05212384) and PF-04691502 against ovarian cancer xenograft models

Simon P. Langdon, Charlene Kay, In Hwa Um, +6

Scientific Reports

Genome-scale CRISPR/Cas9 screen determines factors modulating sensitivity to ProTide NUC-1031

Awa Sarr, Jennifer Bré, In Hwa Um, +4

Scientific Reports

Spatial Analysis of NQO1 in Non-Small Cell Lung Cancer Shows Its Expression Is Independent of NRF1 and NRF2 in the Tumor Microenvironment

Boback Kaghazchi, In Hwa Um, Mustafa Elshani, +2

Biomolecules

ImmunologyPathologyExpression Is IndependentEarly-stage Nsclc PatientsRedox Biology +15