Bacteroides fragilis restricts colitis-associated cancer via negative regulation of the NLRP3 axis

Xinyu Shao, Shishuo Sun, Yuqing Zhou, +5

Cancer Letters

DysbiosisMicrobial PathogensHost-microbe InteractionsImmunologyGastroenterology +24

Major role of adipocyte prostaglandin E2 in lipolysis-induced macrophage recruitment

Xiaoqian Hu, Vincenza Cifarelli, Shishuo Sun, +3

Journal of Lipid Research

ImmunologyAdipose Tissue MacrophagesAdipokinesObesityMetabolic Syndrome +16

CD36 regulates LPS-induced acute lung injury by promoting macrophages M1 polarization

Shishuo Sun, Yizhou Yao, Chao Huang, +9

Cellular Immunology

Acute Lung InjuryInflammationCytokineInflammatory Lung DiseaseLung Inflammation +8

Fatty acid 2-hydroxylation inhibits tumor growth and increases sensitivity to cisplatin in gastric cancer

Yizhou Yao, Xiaoqin Yang, Liang Sun, +9

EBioMedicine

Lenvatinib promotes antitumor immunity by enhancing the tumor infiltration and activation of NK cells.

Qing Zhang, Hongyan Liu, Hanhan Wang, +7

PubMed

ImmunologyNk CellsAntitumor ImmunityImmunotherapyCancer Biology +14

Akt inhibition at the initial stage of CAR-T preparation enhances the CAR-positive expression rate, memory phenotype and in vivo efficacy.

Qing Zhang, Jiage Ding, Shishuo Sun, +7

PubMed

Infused Car-t CellsT-regulatory CellImmunologyImmunoeditingImmunotherapy +16

Lenvatinib enhances T cell immunity and the efficacy of adoptive chimeric antigen receptor-modified T cells by decreasing myeloid-derived suppressor cells in cancer

Mengmeng Lü, Xiaokang Zhang, Xiaoge Gao, +11

Pharmacological Research

Ubiquitinated CD36 sustains insulin-stimulated Akt activation by stabilizing insulin receptor substrate 1 in myotubes

Shishuo Sun, Pengcheng Tan, Xiaoheng Huang, +4

Journal of Biological Chemistry

ImmunologyScavenger Receptor Cd36Insulin ReceptorCellular PhysiologyInsulin Signaling +15

Roux-en-Y reconstruction alleviates radical gastrectomy-induced colitis via down-regulation of the butyrate/NLRP3 signaling pathway

Yizhou Yao, Shishuo Sun, Jinrong Gu, +7

EBioMedicine

Docetaxel enhances the therapeutic efficacy of PSMA-specific CAR-T cells against prostate cancer models by suppressing MDSCs

Xiaokang Zhang, Shishuo Sun, Yangna Miao, +13

Journal of Cancer Research and Clinical Oncology

UrologyGenitourinary CancerMedicineTherapeutic EfficacyCancer Treatment +5