TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection

Francesca Alfei, Kristiyan Kanev, Maike Hofmann, +17

Nature

Viral PersistenceAutoimmune DiseaseT-regulatory CellImmunologyVirology +5

The use of exome capture RNA-seq for highly degraded RNA with application to clinical cancer sequencing

Marcin Cieślik, Rashmi Chugh, Yi-Mi Wu, +11

Genome Research

EngineeringGeneticsTranscriptomics TechnologyCapture Transcriptome ProfilingGene Expression Profiling +17

Proliferation-competent Tcf1+ CD8 T cells in dysfunctional populations are CD4 T cell help independent

Kristiyan Kanev, Ming Wu, Antar Drews, +4

Proceedings of the National Academy of Sciences

T-regulatory CellImmunologyCd4 T Cell ResponsesImmunotherapySingle Cell Sequencing +15

MicroRNA-664a-5p promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by directly downregulating HMGA2

Yan Zhang, Yue Liu, Ming Wu, +7

Biochemical and Biophysical Research Communications

Regenerative MedicineDevelopmental BiologyMedicineStem Cell ResearchStem-cell Therapy +4

Precursors of exhausted T cells are pre-emptively formed in acute infection

Talyn Chu, Ming Wu, Barbara Höllbacher, +18

Nature

Haplotype-Phased Synthetic Long Reads from Short-Read Sequencing

James A. Stapleton, Jeongwoon Kim, John P. Hamilton, +10

PLoS ONE

GeneticsMolecular BiologyComplex GenomesShort Read LengthsGenomics +15

Targeted resequencing reveals genetic risks in patients with sporadic idiopathic pulmonary fibrosis

Yanhan Deng, Zongzhe Li, Juan Liu, +27

Human Mutation

Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development

Stefanie Scherer, Susanne Oberle, Kristiyan Kanev, +30

Nature Immunology

Signal TransductionMolecular BiologyCell DevelopmentMedicineCell Biology +2

Bioconversion of food waste to crayfish feed using solid-state fermentation with yeast

Qinping Li, Puhong Yi, Jianze Zhang, +7

Environmental Science and Pollution Research

BiomanufacturingEngineeringFood FermentationSolid-state FermentationBiotechnology +6

Combining bioinformatics, network pharmacology and artificial intelligence to predict the mechanism of celastrol in the treatment of type 2 diabetes

Ming Wu, Yan Zhang

Frontiers in Endocrinology