Astragalus saponins induce growth inhibition and apoptosis in human colon cancer cells and tumor xenograft

Mandy M.Y. Tin, C.-H. Cho, Kelvin Chan, +2

Carcinogenesis

Chemoprevention StrategyPathologyCell DeathTumor BiologyOncology +15

An inter‐dimer allosteric switch controls NMDA receptor activity

Jean‐Baptiste Esmenjaud, David Stroebel, Kelvin Chan, +5

The EMBO Journal

Molecular PharmacologyMedicineReceptor (Biochemistry)Molecular BiologyNmda Receptor Activity +2

A Comparative Study on the Inhibitory Effects of Different Parts and Chemical Constituents of Pomegranate on α‐Amylase and α‐Glucosidase

Antony Kam, Kong M. Li, Valentina Razmovski‐Naumovski, +4

Phytotherapy Research

Food ChemistryChemical ConstituentsFood Bioactive CompoundBiochemistryMedicine +13

Danshensu protects against 6-hydroxydopamine-induced damage of PC12 cells in vitro and dopaminergic neurons in zebrafish

Cheong‐Meng Chong, Zhong-Yan Zhou, Valentina Razmovski‐Naumovski, +6

Neuroscience Letters

Pc12 CellsMolecular Neuroscience6-Hydroxydopamine-induced DamageDopaminergic NeuronsNeuroanatomy +11

Application of Complementary and Alternative Medicine on Neurodegenerative Disorders 2013

Siu‐Po Ip, Karl Wah Keung Tsim, Kelvin Chan, +1

Evidence-based Complementary and Alternative Medicine

EducationAcupunctureTreatment DevelopmentAlzheimer's DiseaseSymptomatic Treatment +22

From Omics to Drug Metabolism and High Content Screen of Natural Product in Zebrafish: A New Model for Discovery of Neuroactive Compound

Ming Wai Hung, Zai Jun Zhang, Li Shang, +6

Evidence-based Complementary and Alternative Medicine

NeurotransmitterSystem PharmacologyExperimental PharmacologyNeuroactive CompoundSystems Pharmacology +14

Lupus autoantibodies act as positive allosteric modulators at GluN2A-containing NMDA receptors and impair spatial memory

Kelvin Chan, Tomás Huerta, Noele Certain, +6

Nature Communications

Valeriana amurensis improves Amyloid-beta 1-42 induced cognitive deficit by enhancing cerebral cholinergic function and protecting the brain neurons from apoptosis in mice

Qiuhong Wang, Changfu Wang, Zunpeng Shu, +7

Journal of Ethnopharmacology

The physicochemical properties and the in vivo AChE inhibition of two potential anti-Alzheimer agents, bis(12)-hupyridone and bis(7)-tacrine

Hua Yu, Wen-Ming Li, Kelvin K.W. Kan, +8

Journal of Pharmaceutical and Biomedical Analysis

Medicinal ChemistryAlzheimer's DiseaseMedicineDementiaPharmacological Agent +10

Divergent roles of a peripheral transmembrane segment in AMPA and NMDA receptors

Johansen Amin, Catherine L. Salussolia, Kelvin Chan, +6

The Journal of General Physiology