Chengdan Lai

A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington’s Disease

Sen Yan, Zhuchi Tu, Zhaoming Liu et al. · Cell · 2018 · 339 citations

Life Sciences, Genetics, Neuroscience +14

Efficient base editing for multiple genes and loci in pigs using base editors

Jingke Xie, Weikai Ge, Nan Li et al. · Nature Communications · 2019 · 131 citations · Full text

Life Sciences, Biotechnology, Genetics +16

Cre-dependent Cas9-expressing pigs enable efficient in vivo genome editing

Kepin Wang, Qin Jin, Degong Ruan et al. · Genome Research · 2017 · 76 citations · Full text

Life Sciences, Biotechnology, Genetics +13

XIST Derepression in Active X Chromosome Hinders Pig Somatic Cell Nuclear Transfer

Degong Ruan, Jiangyun Peng, Xiaoshan Wang et al. · Stem Cell Reports · 2018 · 69 citations · Full text

Life Sciences, Developmental Biology, Genetics +17

AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patterns

Yanhui Liang, Jingke Xie, Quanjun Zhang et al. · Nucleic Acids Research · 2022 · 64 citations · Full text

Life Sciences, Genetics, Molecular Biology +14