Gut microbiota mediates intermittent-fasting alleviation of diabetes-induced cognitive impairment

Zhigang Liu, Xiaoshuang Dai, Hongbo Zhang, +22

Nature Communications

DysbiosisHost-microbe InteractionsGut MicrobiotaMetabolic RemodelingMetabolic Syndrome +18

ApoE4 Impairs Neuron-Astrocyte Coupling of Fatty Acid Metabolism

Guoyuan Qi, Yashi Mi, Xiaojian Shi, +3

Cell Reports

Lipid PeroxidationRisk Gene Apoe4Oxidative StressAlzheimer's DiseaseBrain Lipid Homeostasis +14

High-fiber diet mitigates maternal obesity-induced cognitive and social dysfunction in the offspring via gut-brain axis

Xiaoning Liu, Xiang Li, Bing Xia, +16

Cell Metabolism

ObesityNutritionBehavioral SciencesBehavioral NeurosciencePublic Health Nutrition +13

Loss of fatty acid degradation by astrocytic mitochondria triggers neuroinflammation and neurodegeneration

Yashi Mi, Guoyuan Qi, Francesca Vitali, +7

Nature Metabolism

Metabolic SyndromeMitophagyNeurodegenerative DiseasesMitochondrial FunctionFatty Acid Degradation +9

Monoamine oxidase A mediates prostate tumorigenesis and cancer metastasis

Jason Wu, Chen Shao, Xiangyan Li, +11

Journal of Clinical Investigation

Cancer MetastasisCancer BiologyTumor BiologyOxidative StressProstate Tumor Growth +14

High-Fat Diet Induces Hepatic Insulin Resistance and Impairment of Synaptic Plasticity

Zhigang Liu, Ishan Patil, Tianyi Jiang, +5

PLoS ONE

NutritionBrain NutritionHigh-fat DietFatty Liver DiseaseInsulin Signaling +16

Erianin induces G2/M-phase arrest, apoptosis, and autophagy via the ROS/JNK signaling pathway in human osteosarcoma cells in vitro and in vivo

Hui Wang, Tie‐Ning Zhang, Weijie Sun, +8

Cell Death and Disease

The anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis

Zeze Fu, Biyong Deng, Yuxin Liao, +6

BMC Cancer

White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease

Lauren Klosinski, Jia Yao, Fei Yin, +5

EBioMedicine

Arsenic sulfide induces apoptosis and autophagy through the activation of ROS/JNK and suppression of Akt/mTOR signaling pathways in osteosarcoma

Gangyang Wang, Tao Zhang, Wei Sun, +11

Free Radical Biology and Medicine

Cancer ResearchMitophagyCell AutophagyApoptosisAutophagy +7