Olivier Lacombe

Design, Synthesis, and Evaluation of a Novel Series of Indole Sulfonamide Peroxisome Proliferator Activated Receptor (PPAR) α/γ/δ Triple Activators: Discovery of Lanifibranor, a New Antifibrotic Clinical Candidate

Benaı̈ssa Boubia, Olivia Poupardin, Martine Barth et al. · Journal of Medicinal Chemistry · 2018 · 106 citations · Full text

Pharmaceutical Science, Pharmacotherapy, Pharmaceutical Chemistry +19

<i>In Vitro</i>Primary Human and Animal Cell-Based Blood−Brain Barrier Models as a Screening Tool in Drug Discovery

Olivier Lacombe, Orianne Videau, Delphine Chevillon et al. · Molecular Pharmaceutics · 2011 · 63 citations

Localisation of drug permeability along the rat small intestine, using markers of the paracellular, transcellular and some transporter routes

Olivier Lacombe, John M. Woodley, Claude Solleux et al. · European Journal of Pharmaceutical Sciences · 2004 · 51 citations

Medicine, Membrane Transport, Physiology +9

The pan-PPAR agonist lanifibranor reduces development of lung fibrosis and attenuates cardiorespiratory manifestations in a transgenic mouse model of systemic sclerosis

Emma Derrett‐Smith, Kristina E N Clark, Shiwen Xu et al. · Arthritis Research & Therapy · 2021 · 24 citations · Full text

Odiparcil, a potential glycosaminoglycans clearance therapy in mucopolysaccharidosis VI—Evidence from in vitro and in vivo models

Eugeni V. Entchev, Ingrid Jantzen, Philippe Masson et al. · PLoS ONE · 2020 · 21 citations · Full text