Steven C. Griffen

Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans

Kimber L. Stanhope, Jean Marc Schwarz, Nancy L. Keim et al. · Journal of Clinical Investigation · 2009 · 1.7K citations · Full text

Life Sciences, Nutrition, Nutritional Sciences +17

Increased Toll-Like Receptor (TLR) 2 and TLR4 Expression in Monocytes from Patients with Type 1 Diabetes: Further Evidence of a Proinflammatory State

Sridevi Devaraj, Mohan R. Dasu, Jason Rockwood et al. · The Journal of Clinical Endocrinology & Metabolism · 2007 · 372 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes (DEPICT-1): 24 week results from a multicentre, double-blind, phase 3, randomised controlled trial

Paresh Dandona, Chantal Mathieu, Moshe Phillip et al. · The Lancet Diabetes & Endocrinology · 2017 · 292 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +10

Characterization of Renal Glucose Reabsorption in Response to Dapagliflozin in Healthy Subjects and Subjects With Type 2 Diabetes

Ralph A. DeFronzo, Marcus Hompesch, Sreeneeranj Kasichayanula et al. · Diabetes Care · 2013 · 288 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +17

Exploring the Potential of the SGLT2 Inhibitor Dapagliflozin in Type 1 Diabetes: A Randomized, Double-Blind, Placebo-Controlled Pilot Study

Robert R. Henry, Julio Rosenstock, Steven V. Edelman et al. · Diabetes Care · 2014 · 237 citations

Medicine, Pharmacology, Pharmacotherapy +15