Betty Lam

Discovery of TAK-659 an orally available investigational inhibitor of Spleen Tyrosine Kinase (SYK)

Betty Lam, Yasuyoshi Arikawa, Joshua Cramlett et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 60 citations · Full text

Biochemistry, Available Investigational Inhibitor, Medicine +7

Discovery of TAK-041: a Potent and Selective GPR139 Agonist Explored for the Treatment of Negative Symptoms Associated with Schizophrenia

H Reichard, Hans H. Schiffer, Holger Monenschein et al. · Journal of Medicinal Chemistry · 2021 · 35 citations · Full text

Structure-based design of pyridopyrimidinediones as dipeptidyl peptidase IV inhibitors

Betty Lam, Zhiyuan Zhang, Jeffery A. Stafford et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 23 citations · Full text

Medicine, Peptoid, Rational Drug Design +3

Structure-based design and SAR development of 5,6-dihydroimidazolo[1,5-f]pteridine derivatives as novel Polo-like kinase-1 inhibitors

Andre A. Kiryanov, Srinivasa Reddy Natala, Benjamin Jones et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 18 citations · Full text

Combinatorial Chemistry, Sar Development, Medicinal Chemistry +9