Targeting the Metabolic Plasticity of Multiple Myeloma with FDA-Approved Ritonavir and Metformin

Sevim Dalva-Aydemir, Richa Bajpai, Maylyn Martinez, +8

Clinical Cancer Research

Subpopulation targeting of pyruvate dehydrogenase and GLUT1 decouples metabolic heterogeneity during collective cancer cell invasion

Rachel Commander, Changyong Wei, Aditi Sharma, +11

Nature Communications

Targeting glutamine metabolism in multiple myeloma enhances BIM binding to BCL-2 eliciting synthetic lethality to venetoclax

Richa Bajpai, Shannon M. Matulis, Changyong Wei, +5

Oncogene

Hematological MalignancyGlutamine MetabolismMedicineMalignant Blood DisorderImmunology +8

Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma

Richa Bajpai, Aditi Sharma, Abhinav Achreja, +14

Nature Communications

In Silico Modeling-based Identification of Glucose Transporter 4 (GLUT4)-selective Inhibitors for Cancer Therapy

Rama K. Mishra, Changyong Wei, Richard C. Hresko, +8

Journal of Biological Chemistry

Molecular DockingCancer TherapySilico Modeling-based IdentificationDrug TargetBiochemistry +7

PSMB8 regulates glioma cell migration, proliferation, and apoptosis through modulating ERK1/2 and PI3K/AKT signaling pathways

Bingya Yang, Jingwei Song, Hongzhi Sun, +12

Biomedicine & Pharmacotherapy

RRM2 is a potential prognostic biomarker with functional significance in glioma

Hongzhi Sun, Bingya Yang, Hao Zhang, +11

International Journal of Biological Sciences

Development of GLUT4-selective antagonists for multiple myeloma therapy

Changyong Wei, Richa Bajpai, Horrick Sharma, +8

European Journal of Medicinal Chemistry

Hematological MalignancyMedicineMalignant Blood DisorderPharmacotherapyImmunotherapy +3

Transcriptional Factors Smad1 and Smad9 Act Redundantly to Mediate Zebrafish Ventral Specification Downstream of Smad5

Changyong Wei, Hou-Peng Wang, Zuoyan Zhu, +1

Journal of Biological Chemistry

Marcksb plays a key role in the secretory pathway of zebrafish Bmp2b

Ye Ding, Xiaosi Wang, Changyong Wei, +5

PLoS Genetics

Bmp-producing CellsProtein SecretionSclerostinKey RoleEmbryology +15