Aging and Replicative Senescence Have Related Effects on Human Stem and Progenitor Cells

Wolfgang Wagner, Simone Bork, Patrick Horn, +9

PLoS ONE

Progenitor CellsAgingGeneticsAdult Stem CellBiogerontology +17

Co‐culture with mesenchymal stromal cells increases proliferation and maintenance of haematopoietic progenitor cells

Thomas Walenda, Simone Bork, Patrick Horn, +6

Journal of Cellular and Molecular Medicine

Impact of individual platelet lysates on isolation and growth of human mesenchymal stromal cells

Patrick Horn, Gudrun Bokermann, Dominik Cholewa, +8

Cytotherapy

Regenerative MedicineThrombopoiesisDevelopmental BiologyBlood PlateletIndividual Platelet Lysates +7

Isolation of human mesenchymal stromal cells is more efficient by red blood cell lysis

Patrick Horn, Simone Bork, Anke Diehlmann, +4

Cytotherapy

Regenerative MedicineCell TherapyMedicineHematologyBlood Cell +6

Expansion of Adipose Mesenchymal Stromal Cells is Affected by Human Platelet Lysate and Plating Density

Dominik Cholewa, Thomas Stiehl, Anne Schellenberg, +8

Cell Transplantation

Synergistic effects of growth factors and mesenchymal stromal cells for expansion of hematopoietic stem and progenitor cells

Thomas Walenda, Gudrun Bokermann, Mónica S. Ventura Ferreira, +6

Experimental Hematology

Progenitor CellsRegenerative MedicineDevelopmental BiologyMedicineStem Cell Mobilization +10

N-Cadherin is expressed on human hematopoietic progenitor cells and mediates interaction with human mesenchymal stromal cells

Frederik Wein, Larissa Pietsch, Rainer Saffrich, +8

Stem Cell Research

Mediates InteractionMedicineCell InteractionImmunologyHematology +7

Epimutations mimic genomic mutations of DNMT3A in acute myeloid leukemia

Edgar Jost, Qiong Lin, Carola I. Weidner, +9

Leukemia

Histone ModificationsMixed-phenotype Acute LeukemiaGeneticsDna MethylationEpigenetic Change +15

Feedback Signals in Myelodysplastic Syndromes: Increased Self-Renewal of the Malignant Clone Suppresses Normal Hematopoiesis

Thomas Walenda, Thomas Stiehl, Hanna Braun, +8

PLoS Computational Biology

Hematopoietic Stem and Progenitor Cells Acquire Distinct DNA-Hypermethylation During in vitro Culture

Carola I. Weidner, Thomas Walenda, Qiong Lin, +5

Scientific Reports