Jeffery L. Cornelison

Development of the First Low Nanomolar Liver Receptor Homolog-1 Agonist through Structure-guided Design

Suzanne G. Mays, Autumn R. Flynn, Jeffery L. Cornelison et al. · Journal of Medicinal Chemistry · 2019 · 31 citations · Full text

Engineering, Biomedical Engineering, Nanomedicine +17

Development of a new class of liver receptor homolog-1 (LRH-1) agonists by photoredox conjugate addition

Jeffery L. Cornelison, Michael L. Cato, Alyssa M. Johnson et al. · Bioorganic & Medicinal Chemistry Letters · 2020 · 20 citations · Full text

Optogenetics, Liver Receptor Homolog-1, Signal Transduction +12

A phospholipid mimetic targeting LRH-1 ameliorates colitis

Suzanne G. Mays, Emma H. D’Agostino, Autumn R. Flynn et al. · Cell chemical biology · 2022 · 15 citations · Full text

Inflammation, Anti-inflammatory, Medicine +4

Development of a Versatile and Sensitive Direct Ligand Binding Assay for Human NR5A Nuclear Receptors

Emma H. D’Agostino, Autumn R. Flynn, Jeffery L. Cornelison et al. · ACS Medicinal Chemistry Letters · 2019 · 13 citations · Full text

Nuclear Receptor 5A, Drug Target, Signal Transduction +14

Differential Modulation of Nuclear Receptor LRH-1 through Targeting Buried and Surface Regions of the Binding Pocket

Michael L. Cato, Jeffery L. Cornelison, Racheal M. Spurlin et al. · Journal of Medicinal Chemistry · 2022 · 12 citations · Full text