Christine Wedler

Synthesis of Enantiomerically Pure β-Lactones by the Tandem Aldol−Lactonization. A Highly Efficient Access to (3<i>S</i>,4<i>S</i>)-3-Hexyl-4- [(2<i>S</i>)-2-hydroxytridecyl]oxetan-2-one, the Key Intermediate for the Enzyme Inhibitors Tetrahydrolipstatin and Tetrahydroesterastin^,¹

Christine Wedler, Burckhard Costisella, Hans Schick · The Journal of Organic Chemistry · 1999 · 30 citations

Life Sciences, Pharmacology, Drug Discovery +6

Synthesis of .beta.-Lactones via a Spontaneous Intramolecular Cyclization of O-Lithiated Phenyl .beta.-Hydroxyalkanoates Obtained by Aldolization of Ketones or Aldehydes with Lithium Enolates of Phenyl Esters

Christine Wedler, Annamarie Kunath, Hans Schick · The Journal of Organic Chemistry · 1995 · 24 citations

Natural Sciences, Chemistry, Natural Product Biosynthesis +6

Syntheses of β‐Lactones, 6. One‐Step Synthesis of β‐Lactones by Aldolization of Ketones or Aldehydes with 1‐Acylbenzotriazoles

Christine Wedler, Katharina Kleiner, Annamarie Kunath et al. · Liebigs Annalen · 1996 · 18 citations

Natural Sciences, Chemistry, Medicinal Chemistry +12

Reactions of 4‐oxoalkanoic acids. III. Synthesis of 5‐Methyl‐ and 5‐Methylenepyrrolidin‐2‐ones by reaction of α‐angelica lactone with methylamine

Christine Wedler, Burkhard Costisella, Hans Schick · Journal für praktische Chemie · 1990 · 12 citations

Pharmacy, Medicinal Chemistry, Drug Discovery +5

Unexpected Course of the Darzens Reaction of Phenyl Esters of α‐Chlorocarboxylic Acids with Carbonyl Compounds–A Novel One‐Step Synthesis of α‐Chloro‐β‐lactones

Christine Wedler, Annamarie Kunath, Hans Schick · Angewandte Chemie International Edition in English · 1995 · 11 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9