Synthesis of Enantiomerically Pure β-Lactones by the Tandem Aldol−Lactonization. A Highly Efficient Access to (3<i>S</i>,4<i>S</i>)-3-Hexyl-4- [(2<i>S</i>)-2-hydroxytridecyl]oxetan-2-one, the Key Intermediate for the Enzyme Inhibitors Tetrahydrolipstatin and Tetrahydroesterastin^,¹

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTSynthesis of Enantiomerically Pure β-Lactones by the Tandem Aldol−Lactonization. A Highly Efficient Access to (3S,4S)-3-Hexyl-4- [(2S)-2-hydroxytridecyl]oxetan-2-one, the Key Intermediate for the Enzyme Inhibitors Tetrahydrolipstatin and Tetrahydroesterastin†,1Christine Wedler, Burckhard Costisella, and Hans SchickView Author Information WITEGA Angewandte Werkstoff-Forschung g. GmbH, Rudower Chaussee 5, D-12484 Berlin, Germany Cite this: J. Org. Chem. 1999, 64, 14, 5301–5303Publication Date (Web):June 24, 1999Publication History Received18 February 1998Published online24 June 1999Published inissue 1 July 1999https://pubs.acs.org/doi/10.1021/jo980292ahttps://doi.org/10.1021/jo980292abrief-reportACS PublicationsCopyright © 1999 American Chemical SocietyRequest reuse permissionsArticle Views630Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Aldehydes,Alkyls,Inhibitors,Organic compounds,Peptides and proteins Get e-Alerts