Tara Spence

Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR

Claudia L. Kleinman, Noha Gerges, Simon Papillon‐Cavanagh et al. · Nature Genetics · 2013 · 195 citations · Full text

Brain-specific Dnmt3b Isoform, Developmental Biology, Epigenetic Change +7

Heterogenous loss of mismatch repair (MMR) protein expression: a challenge for immunohistochemical interpretation and microsatellite instability (MSI) evaluation

Aoife J McCarthy, José‐Mario Capo‐Chichi, Tara Spence et al. · The Journal of Pathology Clinical Research · 2018 · 160 citations · Full text

Genetics, Immunology, Pathology +20

CNS-PNETs with C19MC amplification and/or LIN28 expression comprise a distinct histogenetic diagnostic and therapeutic entity

Tara Spence, Patrick Sin‐Chan, Daniel Picard et al. · Acta Neuropathologica · 2014 · 158 citations · Full text

A novel C19MC amplified cell line links Lin28/let-7 to mTOR signaling in embryonal tumor with multilayered rosettes

Tara Spence, Christian Perotti, Patrick Sin‐Chan et al. · Neuro-Oncology · 2013 · 64 citations · Full text

Hyperthermia-mediated drug delivery induces biological effects at the tumor and molecular levels that improve cisplatin efficacy in triple negative breast cancer

Michael Dunne, Yannan N. Dou, Danielle M. Drake et al. · Journal of Controlled Release · 2018 · 44 citations

Oncology, Biological Effects, Cisplatin Efficacy +11