Patrick Sin‐Chan

Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

Stephen C. Mack, Hendrik Witt, Rosario M. Piro et al. · Nature · 2014 · 610 citations · Full text

Developmental Anomaly, Epigenomic Alterations, Developmental Biology +8

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors

Jonathon Torchia, Brian Golbourn, Shengrui Feng et al. · Cancer Cell · 2016 · 251 citations · Full text

Tumor Biology, Radiation Oncology, Neuro-oncology +11

Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling

Stephen C. Mack, Kristian W. Pajtler, Lukas Chávez et al. · Nature · 2017 · 223 citations · Full text

Oncology, Novel Therapy, Oncogenic Agent +7

Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR

Claudia L. Kleinman, Noha Gerges, Simon Papillon‐Cavanagh et al. · Nature Genetics · 2013 · 195 citations · Full text

Brain-specific Dnmt3b Isoform, Developmental Biology, Epigenetic Change +7

Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis

Jonathon Torchia, Daniel Picard, Lucie Lafay‐Cousin et al. · The Lancet Oncology · 2015 · 179 citations

Tumoral Pathology, Tumor Heterogeneity, Medicine +9