Itaru Urakawa

Klotho converts canonical FGF receptor into a specific receptor for FGF23

Itaru Urakawa, Yuji Yamazaki, Takashi Shimada et al. · Nature · 2006 · 1.8K citations

Signal Transduction, Signaling Pathway, G Protein-coupled Receptor +10

Establishment of sandwich ELISA for soluble alpha-Klotho measurement: Age-dependent change of soluble alpha-Klotho levels in healthy subjects

Y. Yamazaki, Akihiro Imura, Itaru Urakawa et al. · Biochemical and Biophysical Research Communications · 2010 · 485 citations · Full text

Allergy, Healthy Subjects, Medicine +5

Mutant FGF-23 Responsible for Autosomal Dominant Hypophosphatemic Rickets Is Resistant to Proteolytic Cleavage and Causes Hypophosphatemia in Vivo

Takashi Shimada, Takanori Muto, Itaru Urakawa et al. · Endocrinology · 2002 · 432 citations · Full text

Phosphate Metabolism, Sclerostin, Pathology +24

FGF-23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type IIa

Takashi Shimada, Itaru Urakawa, Y. Yamazaki et al. · Biochemical and Biophysical Research Communications · 2004 · 429 citations

Molecular Physiology, Signal Transduction, Reduced Expression +9

Vitamin D receptor-independent FGF23 actions in regulating phosphate and vitamin D metabolism

Takashi Shimada, Y. Yamazaki, M Takahashi et al. · American Journal of Physiology-Renal Physiology · 2005 · 356 citations

Phosphate Metabolism, Vitamin D Metabolism, Renal Inflammation +21