Itaru Urakawa

Klotho converts canonical FGF receptor into a specific receptor for FGF23

Itaru Urakawa, Yuji Yamazaki, Takashi Shimada et al. · Nature · 2006 · 1.8K citations

Life Sciences, Genetics, Molecular Biology +10

Establishment of sandwich ELISA for soluble alpha-Klotho measurement: Age-dependent change of soluble alpha-Klotho levels in healthy subjects

Y. Yamazaki, Akihiro Imura, Itaru Urakawa et al. · Biochemical and Biophysical Research Communications · 2010 · 496 citations · Full text

Life Sciences, Biochemistry, Clinical Biochemistry +6

Mutant FGF-23 Responsible for Autosomal Dominant Hypophosphatemic Rickets Is Resistant to Proteolytic Cleavage and Causes Hypophosphatemia in Vivo

Takashi Shimada, Takanori Muto, Itaru Urakawa et al. · Endocrinology · 2002 · 437 citations

Medicine, Biochemistry, Molecular Biology +17

FGF-23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type IIa

Takashi Shimada, Itaru Urakawa, Y. Yamazaki et al. · Biochemical and Biophysical Research Communications · 2004 · 431 citations

Medicine, Molecular Biology, Physiology +12

Vitamin D receptor-independent FGF23 actions in regulating phosphate and vitamin D metabolism

Takashi Shimada, Y. Yamazaki, M Takahashi et al. · American Journal of Physiology-Renal Physiology · 2005 · 357 citations

Medicine, Endocrinology, Pharmacology +17