The T Cell Leukemia Oncoprotein SCL/tal-1 Is Essential for Development of All Hematopoietic Lineages

Catherine Porcher, Wojciech Swat, Karen Rockwell, +3

Cell

Hematological MalignancyChromatinDevelopmental BiologyLymphocyte DevelopmentMixed-phenotype Acute Leukemia +7

Coexistence of LMPP-like and GMP-like Leukemia Stem Cells in Acute Myeloid Leukemia

Nicolas Goardon, Emanuele Marchi, Ann Atzberger, +31

Cancer Cell

Hematological MalignancyDevelopmental BiologyMedicineAcute Myeloid LeukemiaMixed-phenotype Acute Leukemia +7

Single-cell analysis reveals the continuum of human lympho-myeloid progenitor cells

Dimitris Karamitros, Bilyana Stoilova, Zahra Aboukhalil, +17

Nature Immunology

Human CellSingle Cell SequencingMedicineLymphocyte DevelopmentImmunology +7

Basic fibroblast growth factor positively regulates hematopoietic development

Patrick W. Faloon, Elizabeth Arentson, Alexander R. Kazarov, +4

Development

Developmental BiologySignal TransductionHealth SciencesCell RegulationMedicine +13

Genome-wide identification of TAL1's functional targets: Insights into its mechanisms of action in primary erythroid cells

Mira Kassouf, Jim R. Hughes, Stephen Taylor, +5

Genome Research

GeneticsGenomic MechanismGene Regulatory NetworkTranscriptional RegulationLineage Maturation +15

Specification of hematopoietic and vascular development by the bHLH transcription factor SCL without direct DNA binding

Catherine Porcher, Eric C. Liao, Yuko Fujiwara, +2

Development

Lymphocyte DevelopmentMixed-phenotype Acute LeukemiaGeneticsBlood CellEpigenetics +18

Porphobilinogen deaminase deficiency in mice causes a neuropathy resembling that of human hepatic porphyria

Raija L.P. Lindberg, Catherine Porcher, Bernard Grandchamp, +5

Nature Genetics

PhysiologyPathologyNeuropathy ResemblingPorphobilinogen Deaminase DeficiencyNeuropathology +3

Genetically distinct leukemic stem cells in human CD34− acute myeloid leukemia are arrested at a hemopoietic precursor-like stage

Lynn Quek, Georg Otto, Catherine Garnett, +30

The Journal of Experimental Medicine

Cell Surface Cd34Mixed-phenotype Acute LeukemiaLsc Differentiation ArrestStem Cell BiologyTumor Biology +16

ETO-2 Associates with SCL in Erythroid Cells and Megakaryocytes and Provides Repressor Functions in Erythropoiesis

Anna Schuh, Alex J. Tipping, Allison J. Clark, +8

Molecular and Cellular Biology

Lineage SpecificationCellular PhysiologyInflammationTranscriptional RegulationErythroid Cells +15

A simplified method for determination of specific DNA or RNA copy number using quantitative PCR and an automatic DNA sequencer.

Catherine Porcher, Marie‐Claire Malinge, C. Picat, +1

PubMed

GeneticsDna AnalysisMolecular BiologyNucleic Acid Amplification TestMolecular Genetics +23