Ruben van Doorn

Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling

Gerty Schreibelt, Gijs Kooij, Arie Reijerkerk et al. · The FASEB Journal · 2007 · 347 citations

Pi3 Kinase, Immunology, Bbb Integrity +29

Sphingosine 1‐phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions

Ruben van Doorn, Jack van Horssen, Dennis Verzijl et al. · Glia · 2010 · 204 citations

Sphingosine 1-phosphate receptor 5 mediates the immune quiescence of the human brain endothelial barrier

Ruben van Doorn, Melissa A Lopes Pinheiro, Gijs Kooij et al. · Journal of Neuroinflammation · 2012 · 124 citations · Full text

Fingolimod attenuates ceramide-induced blood–brain barrier dysfunction in multiple sclerosis by targeting reactive astrocytes

Ruben van Doorn, Philip G. Nijland, Nick Dekker et al. · Acta Neuropathologica · 2012 · 119 citations

Synaptic Signaling, Social Sciences, Neuroinflammation +17

Noninvasive diagnosis of ruptured peripheral atherosclerotic lesions and myocardial infarction by antibody profiling

Kitty B.J.M. Cleutjens, Birgit Faber, Mat Rousch et al. · Journal of Clinical Investigation · 2008 · 20 citations · Full text

Vascular Disease, Heart Failure, Immunology +22