Gary J. Litherland

Ceramide impairs the insulin-dependent membrane recruitment of Protein Kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells

Éric Hajduch, Anudharan Balendran, Ian H. Batty et al. · Diabetologia · 2001 · 229 citations · Full text

Molecular Physiology, Signal Transduction, Biochemistry +15

Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases

Hui Wang, Gary J. Litherland, Martina S. Elias et al. · Annals of the Rheumatic Diseases · 2011 · 209 citations

Regulation of Glucose Transport and Glycogen Synthesis in L6 Muscle Cells during Oxidative Stress

Anne S. Blair, Éric Hajduch, Gary J. Litherland et al. · Journal of Biological Chemistry · 1999 · 166 citations · Full text

Metabolic Remodeling, Redox Biology, Cellular Physiology +21

Key Role for Ceramides in Mediating Insulin Resistance in Human Muscle Cells

Laura Pickersgill, Gary J. Litherland, Andrew S. Greenberg et al. · Journal of Biological Chemistry · 2007 · 143 citations · Full text

Key Role, Cellular Physiology, Insulin Signaling +21

HDAC-mediated control of ERK- and PI3K-dependent TGF-β-induced extracellular matrix-regulating genes

Matt J. Barter, Leon P. Pybus, Gary J. Litherland et al. · Matrix Biology · 2010 · 88 citations

Transcriptional Regulation, Signal Transduction, Signaling Pathway +9