Encapsulation of Acyclovir in new carboxylated cyclodextrin-based nanosponges improves the agent's antiviral efficacy

David Lembo, Shankar Swaminathan, Manuela Donalisio, +6

International Journal of Pharmaceutics

NanomedicineEngineeringMedicineCyclodextrin ProductionCyclodextrin-based Nanosponges +8

Nanomedicine formulations for the delivery of antiviral drugs: a promising solution for the treatment of viral infections

David Lembo, Manuela Donalisio, Andrea Civra, +2

Expert Opinion on Drug Delivery

Preparation and characterization of dextran nanobubbles for oxygen delivery

Roberta Cavalli, Agnese Bisazza, Pierangela Giustetto, +5

International Journal of Pharmaceutics

NanomedicineEngineeringNano-drug DeliveryBiomedical EngineeringDextran Nanobubbles

Additives for vaccine storage to improve thermal stability of adenoviruses from hours to months

Maria Pelliccia, Patrizia Andreozzi, Jayson Paulose, +14

Nature Communications

Inhibition of pathogenic non-enveloped viruses by 25-hydroxycholesterol and 27-hydroxycholesterol

Andrea Civra, Valeria Cagno, Manuela Donalisio, +4

Scientific Reports

The cholesterol metabolite 27-hydroxycholesterol inhibits SARS-CoV-2 and is markedly decreased in COVID-19 patients

Alessandro Marcello, Andrea Civra, Rafaela Milan Bonotto, +10

Redox Biology

Enhanced antiviral activity of Acyclovir loaded into β-cyclodextrin-poly(4-acryloylmorpholine) conjugate nanoparticles

Roberta Cavalli, Manuela Donalisio, Andrea Civra, +4

Journal of Controlled Release

NanomedicineEngineeringPolymer-drug ConjugateAntiviral Drug DevelopmentConjugate Nanoparticles +4

Acyclovir-Loaded Chitosan Nanospheres from Nano-Emulsion Templating for the Topical Treatment of Herpesviruses Infections

Manuela Donalisio, Federica Leone, Andrea Civra, +4

Pharmaceutics

NanoparticlesTissue EngineeringEngineeringBiomedical EngineeringDermatology +15

25-Hydroxycholesterol and 27-hydroxycholesterol inhibit human rotavirus infection by sequestering viral particles into late endosomes

Andrea Civra, Rachele Francese, Paola Gamba, +4

Redox Biology

Identification of a Dendrimeric Heparan Sulfate-Binding Peptide That Inhibits Infectivity of Genital Types of Human Papillomaviruses

Manuela Donalisio, Marco Rusnati, Andrea Civra, +6

Antimicrobial Agents and Chemotherapy