Laura M. McLane

Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8 + T Cell Exhaustion

Bertram Bengsch, Andrew L. Johnson, Makoto Kurachi et al. · Immunity · 2016 · 775 citations · Full text

Metabolic Alterations, Bioenergetic Insufficiencies Due, Signal Transduction +15

TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision

Zeyu Chen, Zhicheng Ji, Shin Foong Ngiow et al. · Immunity · 2019 · 663 citations · Full text

Transcriptional Regulation, Signal Transduction, T-regulatory Cell +9

Characterization of T-Bet and Eomes in Peripheral Human Immune Cells

James J. Knox, Gabriela L. Cosma, Michael R. Betts et al. · Frontiers in Immunology · 2014 · 185 citations · Full text

Lymphocyte Development, Adaptive Immune System, T-regulatory Cell +23

Differential Localization of T-bet and Eomes in CD8 T Cell Memory Populations

Laura M. McLane, Pinaki P. Banerjee, Gabriela L. Cosma et al. · The Journal of Immunology · 2013 · 131 citations · Full text

Chromatin, Transcriptional Regulation, Immunological Memory +15

Role of nuclear localization in the regulation and function of T-bet and Eomes in exhausted CD8 T cells

Laura M. McLane, Shin Foong Ngiow, Zeyu Chen et al. · Cell Reports · 2021 · 118 citations · Full text