Laura M. McLane

Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8 + T Cell Exhaustion

Bertram Bengsch, Makoto Kurachi, Pamela M. Odorizzi et al. · Immunity · 2016 · 829 citations · Full text

Life Sciences, Cell Biology, Immunology +17

TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision

Zeyu Chen, Zhicheng Ji, Shin Foong Ngiow et al. · Immunity · 2019 · 711 citations · Full text

Life Sciences, Immunology, Molecular Biology +12

Characterization of T-Bet and Eomes in Peripheral Human Immune Cells

James J. Knox, Gabriela L. Cosma, Michael R. Betts et al. · Frontiers in Immunology · 2014 · 189 citations · Full text

Life Sciences, Cell Biology, Immunology +6

Differential Localization of T-bet and Eomes in CD8 T Cell Memory Populations

Laura M. McLane, Pinaki P. Banerjee, Gabriela L. Cosma et al. · The Journal of Immunology · 2013 · 133 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Role of nuclear localization in the regulation and function of T-bet and Eomes in exhausted CD8 T cells

Laura M. McLane, Shin Foong Ngiow, Zeyu Chen et al. · Cell Reports · 2021 · 121 citations · Full text

Life Sciences, Cell Biology, Immunology +17