Ryosuke Yumioka

Effects of acid exposure on the conformation, stability, and aggregation of monoclonal antibodies

Daisuke Ejima, Kouhei Tsumoto, Harumi Fukada et al. · Proteins Structure Function and Bioinformatics · 2006 · 212 citations

Immunocytochemical Technique, Acid Conformation, Immunology +17

Elution of antibodies from a Protein-A column by aqueous arginine solutions

Tsutomu Arakawa, John S. Philo, Kouhei Tsumoto et al. · Protein Expression and Purification · 2004 · 196 citations

Bioanalysis, Immunology, Antibody Screening +10

Arginine as an effective additive in gel permeation chromatography

Daisuke Ejima, Ryosuke Yumioka, Tsutomu Arakawa et al. · Journal of Chromatography A · 2005 · 148 citations

Gas Chromatography, Medicine, Analytical Chemistry +4

Effective elution of antibodies by arginine and arginine derivatives in affinity column chromatography

Daisuke Ejima, Ryosuke Yumioka, Kouhei Tsumoto et al. · Analytical Biochemistry · 2005 · 122 citations

Allergy, Medicine, Bioanalysis +13

Refolding single-chain antibody (scFv) using lauroyl-l-glutamate as a solubilization detergent and arginine as a refolding additive

Motonori Kudou, Daisuke Ejima, Haruna Sato et al. · Protein Expression and Purification · 2010 · 51 citations

Solubilization Detergent, Biochemistry, Natural Sciences +12